Join our team!

We are recruiting motivated graduate students, postdoctoral fellows, and research specialists.

What we offer:

° An inclusive and supportive lab culture devoted to promoting professional growth and helping achieve long-term career goals.

° Direct access to state-of-the-art mass spectrometry tools (lab core expertise).

° Excellent research infrastructure and a collaborative environment, providing expertise and support in a variety of approaches, including next-generation sequencing, microscopy, gene editing, cell sorting, bioinformatics, and more.

° An opportunity to develop and lead exciting projects that align with the lab research interests, such as.:

- Developing quantitative proteomics approaches for subnuclear and single-cell histone modification and protein profiling

- Elucidating how epigenetic landscapes are maintained and regulated in postmitotic cells
- Exploring the role of non-canonical histone variants in chromatin regulation

- Dissecting lifelong changes in chromatin organization in mouse somatic tissues.

What we look for:

° Strong interest in chromatin biology and/or aging research and/or proteomics.

° Creativity, passion for science, strong analytical skills, and the ability to critically and efficiently approach complex and challenging research tasks.

° Excellent communication skills, a proactive approach to teamwork and collective problem-solving, and a determination to take on leadership roles in projects.

° The ideal postdoctoral candidate would have strong expertise in at least one of the following areas:

- Chromatin biochemistry

- Genomics approaches, including ChIP-seq, CUT&RUN, RNA-seq

- Mass spectrometry-based proteomics

- Bioinformatic analysis of high-throughput datasets, including genome-wide binding profiling (ChIP-seq, CUT&RUN), transcriptomic, and proteomics data

- Gene editing, mouse genetics.

How to apply?

Interested in joining the Tvardovskiy Lab? Send an email to Andrey at
(Andrey.Tvardovskiy@PennMedicine.upenn.edu)

Postdoctoral Candidates: send your application as a single PDF, including:

(i) a CV,
(ii) a cover letter (1 page max) outlining your scientific accomplishments, short- and long-term professional goals, and motivation to join the lab, and
(iii) contact details for three referees.

To ensure consideration, the email subject should be titled "PostDoc_Tvardovskiy_Lab_Application_Your_Name."

Graduate Students: Any graduate student at Penn is welcome to apply. To arrange a rotation, please send an email describing your research interests along with a copy of your CV.

Research Specialists: Please apply through the Perelman School of Medicine Careers portal.
Please include a short cover letter outlining your professional goals and motivation for joining the lab.